The male reproductive system is a hotspot for the emergence of new genes, which may explain why more new mutations are passed down from fathers rather than mothers. However, the reason why older fathers tend to pass on more mutations than younger ones has remained unclear. A recent study in Nature Ecology & Evolution by scientists from Rockefeller University sheds light on why older male fruit flies are more likely to transmit mutations to their offspring. This research could provide insight into the risk of inherited diseases in humans.

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